The Chronic Inflammatory Response Syndrome (CIRS) Explained

What is Chronic Inflammatory Response Syndrome?

Chronic inflammatory response syndrome (CIRS) is a long-term inflammation of the body that can lead to many symptoms, such as fatigue and brain fog. It’s also referred to as biotoxin illness. Dr Shoemaker found 37 symptoms in cases with thirteen clusters. CIRS was defined as a finding of 8+ symptom clusters out of 13 clusters.

Building occupants exposed to the indoor air of a water-damaged building can cause a whole body inflammatory state and chronic, complex illness. Indoor air contains a complex mixture of fungi, mycotoxins, bacteria, endotoxins, antigens, lipopolysaccharides and biologically produced volatile compounds.

This state of chronic complex multi-system illness has been coined Chronic Inflammatory Response Syndrome or CIRS.

Do-It-Yourself (DIY) Check for Mould Illness

Online VCS Screening can be a way to check for mold illness. It is a measure of one of the neurologic functions of vision called contrast.

Commonly Misdiagnosed Symptoms

Given CIRS is a multi-system, multi-organ and multi-symptom illness, unless your medical practitioner is familiar with the disease, misdiagnosis may occur. This creates a longer journey for the individual’s recovery. Some of the more common misdiagnosis are:

  • Fibromyalgia

  • Chronic Fatigue Syndrome

  • Multiple Sclerosis

  • Depression

  • Stress or Post Traumatic Stress Disorder

  • Allergies

  • Somatization

  • Irritable Bowel Syndrome

  • Attention Deficit Disorder

Therefore, it is best to engage a Shoemaker Protocol Certified Physicians,

CIRS Symptoms Clusters

CIRS was defined as a finding of 8+ symptom clusters out of 13 clusters.

  • Cluster1: Fatigue / Chronic Fatigue

  • Cluster2: Muscle & Cognitive Issues – weakness, decreased assimilation of knowledge, body aches, headaches or migraines, light sensitivity

  • Cluster3: Cognitive – Memory Impairment & Decreased Word Fencing

  • Cluster4: Concentration – Difficulty concentrating

  • Cluster5: Pain – joint pain, morning stiffness, cramps

  • Cluster6: Nerve/Skin – unusual skin sensations, tingling,

  • Cluster7: Respiratory – shortness of breath, sinus congestion

  • Cluster8: Various – Cough, Confusion, Excessive thirst

  • Cluster9: Various – appetite swings, difficulty regulating temperature, frequent urination

  • Cluster10: Various – red eyes, blurred vision, mood swings, ice pick pain, night sweats

  • Cluster11: Gastrointestinal and Nerve – numbness, diarrhea, abdominal pain

  • Cluster12: Various – tearing, disorientation, metallic taste

  • Cluster13: Various – static shocks, vertigo

How To Get Treatment for CIRS or Biotoxin Illness

Finding a “Shoemaker Protocol Certified Physicians” to support you during your recovery every step of the way is the best approach to your recovery journey.


How To Find Out If Your Home is Water Damaged

Hire a Building Biologist to conduct an Indoor Air Quality Test and a Mould Inspection and Mould Testing of your home or office.

The Indoor Air Quality Tests / Air Testing will investigate key parameters of the indoor air. These include:

  • Temperature

  • Relative Humidity

  • Carbon Dioxide

  • Air Particles of Different Sizes (these sizes are all inhalable causing throat, nose, and lung issues)

    • PM10 – large particles with a diameter of 10 micrometres or less.

    • PM2.5 – are particles with a diameter of 2.5 micrometres or less

    • PM1.0 – fine particles with a diameter of 1.0 micrometres or less

    • PM0.3 – ultra fine particles with a diameter of 0.3 micrometres or less

Surface Testing for Bacteria and Mould – Building Biologists can test surfaces for microbial activity by measuring the ATP levels of microorganisms. Microorganisms can be mould or bacteria growing on the surface.

Mould Inspections and Mould Testing will inspect and identify water damaged rooms and building materials. This helps identify the cause of the water damage. Once this is done, mould testing can be conducted to determine the level of mould spores in the air (and on surfaces). These mould testing samples will be sent to the laboratory for analysis.